Detalhe da pesquisa
1.
The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations.
Mol Cell
; 69(3): 412-425.e6, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29395063
2.
RBFox2 Binds Nascent RNA to Globally Regulate Polycomb Complex 2 Targeting in Mammalian Genomes.
Mol Cell
; 62(6): 875-889, 2016 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27211866
3.
Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation.
Genes Dev
; 29(19): 2054-66, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26443849
4.
MiR-145 enriched exosomes derived from bone marrow-derived mesenchymal stem cells protects against cerebral ischemia-reperfusion injury through downregulation of FOXO1.
Biochem Biophys Res Commun
; 632: 92-99, 2022 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36206599
5.
BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processing.
Mol Cell
; 56(2): 298-310, 2014 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25263594
6.
Pre-mRNA splicing is facilitated by an optimal RNA polymerase II elongation rate.
Genes Dev
; 28(23): 2663-76, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25452276
7.
The Akt-SRPK-SR Axis Constitutes a Major Pathway in Transducing EGF Signaling to Regulate Alternative Splicing in the Nucleus.
Mol Cell
; 71(5): 872, 2018 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30193100
8.
Genome-wide analysis reveals SR protein cooperation and competition in regulated splicing.
Mol Cell
; 50(2): 223-35, 2013 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23562324
9.
Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.
EMBO J
; 35(10): 1077-97, 2016 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26951610
10.
The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus.
Mol Cell
; 47(3): 422-33, 2012 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22727668
11.
RBFox2 Binds Nascent RNA to Globally Regulate Polycomb Complex 2 Targeting in Mammalian Genomes.
Mol Cell
; 62(6): 982, 2016 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27315558
12.
JMJD6 and U2AF65 co-regulate alternative splicing in both JMJD6 enzymatic activity dependent and independent manner.
Nucleic Acids Res
; 45(6): 3503-3518, 2017 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27899633
13.
Distinct splicing signatures affect converged pathways in myelodysplastic syndrome patients carrying mutations in different splicing regulators.
RNA
; 22(10): 1535-49, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27492256
14.
Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signaling.
Proc Natl Acad Sci U S A
; 112(17): E2139-48, 2015 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25870297
15.
Global analysis of physical and functional RNA targets of hnRNP L reveals distinct sequence and epigenetic features of repressed and enhanced exons.
RNA
; 21(12): 2053-66, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26437669
16.
Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA.
Nature
; 474(7351): 390-4, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21572438
17.
TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells.
Nucleic Acids Res
; 43(18): 9006-16, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26261210
18.
Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function.
Biochem J
; 466(2): 311-22, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25529026
19.
Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration.
Proc Natl Acad Sci U S A
; 110(47): E4530-9, 2013 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24170860
20.
Versatile pathway-centric approach based on high-throughput sequencing to anticancer drug discovery.
Proc Natl Acad Sci U S A
; 109(12): 4609-14, 2012 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22396588